AMPK is the enzyme responsible for maximising available energy resources when times get tough, either through glucose and nutrient starvation or with increased physical exercise. Think of it like a metabolic master switch, when off it's busy building fat cells and storing glucose for later, but when switched on its using up those stored fat and sugar reserves to produce ATP energy. This is one of the main reasons why fasting and exercise are so beneficial for the body, AMPK senses that energy levels are low so tells the body to burn up existing fats and sugars with increased efficiency, improving cellular health. AMPK stands for AMP-activated protein kinase, meaning that when it senses increased AMP levels it switches on to help regulate energy intake and expenditure. By boosting AMPK with supplements such as Berberine and Alpha-Lipoic acid, the metabolism is encouraged to efficiently repair cells and eliminate metabolic waste and fats. As such AMPK is recognized as a key pathway for longevity and healthy aging.